An internal ribosome entry site-YFP-2A-human HBGEF-loxP-Cre-neoR-loxP cassette was introduced in the 3 untranslated region of the gene, downstream of the stop codon. Germline transmission led to the self-excision of the loxP-Cre-NeoR-loxP cassette in male germinal cells leaving the YFP and human diptheria toxin receptor gene. (J:236069)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
Insertion, Intragenic deletion
--
1
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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