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Targeting vector HTGRS6013_A_D10 from the Knock-out Mouse Project inserted an FRT flanked IRES-lacZ-pA cassette linked to a strong splice acceptor signal, together with a loxP flanked neomycin selection cassette into intron 6 and an additional loxP site into intron 7, thus flanking exon 7 with loxP sites. The lacZ and neomycin cassettes was removed via flp-mediated recombination leaving exon 7 floxed. (J:335230)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
