The allele is generated by homologous recombination in embryonic SCs targeting the IRES-CreERT2 cassette into the 3 untranslated region of the Cldn18 gene after exon 5 on chromosome 9. The neomycin selection cassette was removed subsequently. (J:317989)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count