A vector containing ROSA26 homology arms, a CAG promoter, flox stop sequence, and Gaussia luciferase with ASARTDL tail (secreted ER calcium-monitoring protein or SERCaMP) and a FRT-flanked Neomycin gene was inserted into the Gt(ROSA)26Sor locus. The neomycin cassette was removed in the germline via FLP-mediated recombination. (J:340162)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count