LoxP site was inserted into intron 7 together with a self-excision neomycin cassette flanked by Rox sites and a second loxP site was inserted into intron 8. The neomycin cassette was self-excised leaving exon 8 floxed. (J:328987)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count