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The transgene contains the following elements: Igf2 promoter 3 (Rr146; from 162 bp upstream of TSS of exon 3/alternative exon 1 [chr7:142211218 GRCm39] to 74 bp of 5' UTR in exon 3), an Igf2 enhancer from downstream of H19, the luciferase reporter gene and SV40 poly(A) signal sequences. A number of independent lines were generated. The enhancer drives expression in the liver. (J:334634)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
