The targeting construct contains a CAG promoter followed by a loxPStop (neomycin)loxP cassette and a catalytically inactive mutant (E255A) of the human DNA-mutating enzyme APOBEC3B were introduced to intron 1. (J:341577)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
B6(Cg)-Tyrc-2J/J
Targeted
Insertion, Nucleotide substitutions
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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