A gene cassette composed of internal ribosome entry site (IRES), CreERT2 and a neomycin resistance (Neo) gene flanked between a pair of Frt sites was inserted into the 3'UTR region in the sixth exon of the Plvap gene, through the gene targeting method in ES cells. Neo sequence was subsequently removed from the recombinant allele by mating with a Flipper mouse line. (J:328290)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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