The EUCOMM targeting vector PRPGS00036-W-3-B04 was used to create this knock-out allele. The vector replaces exon 4 with an FRT site, lacZ sequence, loxP site, neomycin resistance gene under the control of the human beta-actin promoter, FRT site, and loxP-flanked exon 4. The lacZ and neomycin were removed via flp-mediated recombination. Exon 4 was deleted via cre-mediated recombination. (J:288987)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count