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EN
The EUCOMM targeting vector PRPGS00036-W-3-B04 was used to create this conditional allele. The vector replaces exon 4 with an FRT site, lacZ sequence, loxP site, neomycin resistance gene under the control of the human beta-actin promoter, FRT site, and loxP-flanked exon 4. The lacZ and neomycin were removed via flp-mediated recombination in the ES cells leaving exon 4 floxed. (J:288987)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
