Using CRISPR/Cas9-mediated genome editing, exons 1 and 2 of the C4b gene were targeted to generate C4b indel mutants with >83% frameshift indels. (J:330602)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count