A cDNA sequence encoding a mutant destabilizing form (DD) of bacterial dihydrofolate reductase (ecDHFR; folA) attached to cre recombinase cDNA was inserted into the Fos gene locus at the translation start site. Funder mice were crossed to a germline-active flpe expressing transgenic line to remove the PGK-neo cassette. (J:334497)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count