The targeting vector consisted of one loxP site and FRT-flanked neomycin resistance cassette inserted upstream of exon 3 as well as a F3-flanked puromycin resistance cassette and one loxP site inserted downstream of exon 3. Recombination removed the selection cassette. (J:82809)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count