Exon 1 was flanked by loxP sites and an FRT-flanked neomycin cassette was inserted downstream of the floxed exon. The neomycin cassette was removed via flp-mediated recombination. (J:236346)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count