EUCOMM targeting vector HTGRS6013_A_H08 was used to create this conditional-ready floxed allele. The vector places an FRT site, splice acceptor site, IRES, lacZ cassette, loxP site, neomycin resistance gene cassette, second FRT site and second loxP site upstream of exon 3 and a third loxP site downstream of exon 3. Flp-mediated recombination removed the lacZ and neomycin cassette leaving exon 3 floxed. (J:227816)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
Insertion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top