The transgene insert contains the following elements: 5.8 kb sequence containing Nr5a1 promoter and gene sequence up to and including 5' UTR on exon 2, the lacZ reporter gene, SV40 ply(A) signal sequences and a ~0.6 kb SacI-KpnI restriction fragment from Nr5a1 intron 4 containing a fetal adrenal development-specific Nr5a1 enhancer. (J:334340)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count