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The transgene insert contains the following elements: 1.8 kb sequence from ~3.5kb downstream of Nr5a1 containing a fetal Leydig cell-specific Nr5a1 enhancer, 5.8 kb sequence containing Nr5a1 promoter (modified) and gene sequence up to and including 5' UTR on exon 2, the mCherry reporter gene, and SV40 poly(A) signal sequences. The modification of the promoter entails two point mutations that abolish an LHX9-binding site. (J:334323)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
