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The transgene insert comprises BAC RP23-354G20 (containing Nr5a1 and 106 kb up- and 100 kb downstream) modified as follows: sequence from the Nr5a1 translation start site in exon 2 through part-way into intron 4 was replaced with the EGFP fluorescent reporter gene, SV40 poly(A) signal sequences, an FRT site flanked neomycin resistance gene cassette and a loxP site. The neo cassette was removed through subsequent Flp-mediated recombination. The BAC also contains the 3' end of Nr6a1, Nr6a1os, Nr5a1os, Adgrd2-ps and the 5' end of Psmb7. (J:334323)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
