A Cre sequence was inserted into the beginning of exon 2 of the Prl ORF in a BAC clone (RP23-441I3 BAC) containing the mouse Prl locus with more than 50 kb of upstream and downstream sequences. The PRL start codon was maintained in the Cre ORF such that the protein product was the first of approximately 10 amino acids of PRL, followed by the full Cre recombinase protein. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:295321)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL)F1
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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