A DTR gene was inserted onto the ATG of the Lyz1 gene through homologous recombination in ES cells. The neomycin selection cassette was flanked by Frt recombination sites and excised in vivo by crossing the mice with the general FLP deleter strain. (J:285915)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count