CRISPR/Cas9 technology was used to target Rnf148 for deletion in zygotes containing the Rnf133em1Zuk allele (carrying a 1070 bp deletion) resulting in a double knock-out allele of both Rnf133 and Rnf148. (J:330415)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count