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The transgenic construct consists of the ubiquitous promoter CAG, composed of the cytomegalovirus (CMV) immediate early enhancer and the modified chicken b-actin promoter, a loxP-flanked transcription STOP cassette (LSL) followed by the cDNA of Katushka fluorescent protein (KFP), and a rabbit beta-globin polyadenylation signal. The Katushka expression is driven by the CAG promoter upon Cre recombinase-mediated excision of the floxed STOP cassette. Five founder mice were generated, three of which transmitted germline. Two lines 3 and 13 were established with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:167974)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
