The Bcl6 super-enhancer, located upstream of the gene, was targeted using CRISPR/Cas9 technology, resulting in a 119.258 kb deletion (chr16:23965578-24084835 (GRCm39)). The deletion contains numerous predicted enhancers plus (part of) the Gm52969, Gm32126, and Gm31814 predicted lncRNA genes. (J:333961)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Applicable
Endonuclease-mediated
Intergenic deletion, Intragenic deletion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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