Log In|Sign Up
EN
A TCC to GCG change resulting in a serine to alanine change at amino acid 75 (p.S75A) in exon 2 introduced a non-phosphorylatable mutation. The targeting vector contained 9 kb of mouse Src sequence containing the 2 bp mutation, and a 3.4 kb HSV-tk-neomycin cassette flanked by a 3.2 kb duplication containing a part of the Src sequence. The selection cassette was excised by homologous recombination within the duplication at one allele. (J:279554)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
