The transgene insertion contains the following elements: four copies of sequence from ~5 kb downstream of Atoh1 coding region that contains the first ~322 bp of subregion B of enhancer Rr387 or E0, Hbb basal promoter, the beta-galactosidase reporter gene, and SV40 ploy(A) signal sequences. Reporter gene embryonic expression reflects the expression of the endogenous gene in the dorsal neural tube. (J:60854)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count