The transgene insertion contains the following elements: a SacII-SmaI restriction fragment containing sequence downstream of Atoh1 (which includes enhancer Rr387 or E0), Hbb basal promoter, the beta-galactosidase reporter gene, and SV40 ploy(A) signal sequences. Reporter gene embryonic expression reflects the expression of the endogenous gene in the dorsal neural tube. (J:60854)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count