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A targeting vector containing a loxP-flanked PGK-NEO cassette and a triplicate SV40 polyA sequence, followed by an EGFP-Centrin 1 fusion cassette (cDNA of the human centrin 1 gene, CETN1, fused in frame, with EGFP at the N-terminus) with Bovine Growth Hormone polyA sequence, was inserted into the Gt(ROSA)26Sor locus. Cre-mediated recombination removed the stop cassette allowing for ubiquitous expression. (J:326689)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
