Atoh1 enhancer E2 was targeted with sgRNAs (targeting GAAGTTTCACTGGACACTGGAGG and AATGACAGAGGTCTTGACAGAGG) using CRISPR/Cas9 technology, resulting in a deletion-insertion with an 890 bp deletion (chr6:64750197-64751086 (GRCm39)), including the enhancer, and a 1 bp insertion (C). (J:332270)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Applicable
Endonuclease-mediated
Intergenic deletion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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