Log In|Sign Up
EN
The targeting construct is designed to insert a rox-flanked STOP cassette (RSR) followed by a creERT2 and an FRT-flanked neomycin resistance (neo) cassette into exon 2 of the gene. Expression of CreERT2 driven by the endogenous Gcg gene promoter occurs only after the removal of RSR by Dre recombinase. (J:101977)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
