CRISPR-targeting inserted into the locus a CAG promoter driving expression of a FLAG-tag Streptococcus pyogenes dead Cas9 (dCas9) and FRT-flanked IRES and EGFP reporter gene. Cre-mediated recombination removed the selection cassette. (J:258204)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count