The Nanog/Dppa3 super-enhancer was targeted with an sgRNA (targeting TGCTGGGGCTCATGTGAGCC) using CRISPR/Cas9, resulting in an ~2.85 kb deletion including the enhancer. (J:333571)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count