Using VelociGene technology, exon 1 and 1.6 kb upstream of exon 1 was flanked by loxP sites. An FRT-flanked hygromycin selection cassette was inserted downstream of the floxed region and was removed via flp-mediated recombination. (J:272957)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count