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The insertion comprises human YAC A94G6, modified to flank the CNS-1 (conserved non-coding sequence 1) sequence, between IL4 and IL13, with loxP sites. The CNS-1 sequence was deleted through subsequent cre-mediated recombination. The YAC contains the 3' end of KIF3A, the IL4, IL13, RAD50, IL5, IRF1, IRF1-AS1 and SLC22A5 genes, and the 3' end of SLC22A4. (J:61463)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
