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EN
The transgene consists of the 1,723-bp human CD11b (ITGAM) promoter, a 2,578-bp fragment encoding a rabbit -globin intron and the CreERT2 sequence, a 603-bp transcript-stabilizing WPRE sequence and a 170-bp spanning SV-40 poly(A) sequence. Three founder lines were generated. information and line numbers were not available. The founder line with the most robust and microglia-specific recombination was chosen for further breeding (F9 line). (J:258024)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
