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The allele was generated by introducing a cassette containing a CreERT2 upstream of IRES-nlacZ followed by a FRT-flanked neo cassette (CreERT2-IRES-nLacZ-FRT-neo-FRT) into the ATG translational site in exon 3 of the Prdm1 gene via homologous recombination in embryonic stem (ES) cells. Correctly targeted ES cell clones were transiently transfected with a FLP expression construct to excise the neo cassette. (J:257197)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
