CRISPR/Cas9 technology flanked exon 7 with loxP sites. Embryos were treated with an homology-directed repair (HDR) enhancer, RS-1, to increase knock-in efficiency. (J:315981)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count