The transgene contains HLA-A*02:01 promotor and the coding sequence of a chimeric molecule composed of the HLA-A*02:01 leader segment, the human beta2-m in its mature form, a 15-aa (GGGGS) x 3 linker peptide, the alpha1 alpha2 HLA class I domains, and the H-2 Db alpha3 to cytoplasmic domains. (J:205453)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count