The transgene contains HLA-A*02:01 promotor and the coding sequence of a chimeric molecule composed of the HLA-A*02:01 leader segment, the human beta2-m in its mature form, a 15-aa (GGGGS) x 3 linker peptide, the alpha1 alpha2 HLA class I domains, and the H-2 Db alpha3 to cytoplasmic domains. (J:205453)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x SJL
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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