The entire coding region was flanked by loxP sites. A neomycin resistance cassette and a third loxP site were inserted downstream of the second loxP site. The neomycin resistance cassette was removed via cre-mediated recombination leaving exons 1 and 2 floxed. (J:269490)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count