A creERT2-P2A-EGFP-SV40PA expression cassette was inserted at exon 2 of the Htr6 gene via homologous recombination. The germline insertion disrupted locus. Western blot analysis of 5-HT6R confirmed that the null mutant. (J:333280)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count