The CTCF-binding insulator in the last intron of Igha was deleted and a loxP site flanked neomycin resistance gene cassette was inserted downstream of Igha (but upstream of enhancer 3'RR (Rr152)). The neo cassette was removed through subsequent cre-mediated recombination. (J:242276)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S2/SvPas
Targeted
Insertion, Intragenic deletion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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