Igha promoter Rr361 (~840 bp), (part of) the last intron and exon of human hemoglobin subunit beta (~1100 bp) and a loxP site flanked neomycin resistance gene cassette were inserted downstream of super-enhancer 3'RR (Rr152), between it and Igh super-insulator Rr363. The neo cassette was removed through subsequent cre-mediated recombination. (J:242276)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S2/SvPas
Targeted
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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