The targeting construct inserted an FRT-flanked neomycin resistance cassette with a 5' loxP site downstream of exon 4. An additional loxP site was inserted upstream of exon 3. Flp-mediated recombination removed the selection cassette. (J:271945)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count