The Myc-related CTCF-binding site was mutated from TGGCCAGTAGAGGGCAC to TGGAACGTCTTGAATGC and a loxP site was inserted upstream of the mutation. The mutation prevents this region from acting as an insulator. (J:257088)
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The Myc-related CTCF-binding site was mutated from TGGCCAGTAGAGGGCAC to TGGAACGTCTTGAATGC and a loxP site was inserted upstream of the mutation. The mutation prevents this region from acting as an insulator. (J:257088)