The targeting vector is created using the flp excision system (FLEx). The vector contains from 5'; to 3': lox2272, loxP sites, a FLEx cassette containing the last exon of Ank3 (ENSMUSE00001264329 within ENSMUST00000182992.8), an FRT-flanked neo cassette, a pGHpA sequence, and an EGFP reporter in reverse orientation followed by lox2272 and loxP sites inserted downstream of the endogenous last exon. Flp-mediated recombination removed the neo cassette. (J:333091)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
Insertion
--
1
2
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top