The single exon was replaced with a loxP-flanked Junb exon and an FRT-flanked pgk-neomycin cassette. The neomycin resistance cassette was removed via flp-mediated recombination, leaving the entire open reading frame floxed. (J:287427)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count