A loxP site and FRT-flanked neomycin resistance gene cassette was inserted upstream of exon 2 and a second loxP site was inserted downstream of exon 3. The neomycin gene was removed via flp-mediated recombination leaving exons 2-3 floxed. (J:287473)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count