A targeting vector was designed in which loxP sites were introduced upstream and downstream of the Snap25 exon 4, and a neo cassette flanked with Frt sites as a selectable marker was introduced downstream of exon 4. Flp recombinase to remove the neo cassette. (J:333049)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count