The Cry1 circadian rhythm enhancer in Cry1 intron 1 was targeted with sgRNAs using CRISPR/Cas9 technology, resulting in a 300 bp deletion. The deletion affects Cry1 transcription and transcription of other circadian rhythm related genes. (J:272434)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count