A CAGGS promoter, floxed stop cassette, mutant Prkag1 cDNA encoding D316A mutation, and a sequence encoding the Flag epitope at the C terminus were inserted via homologous recombination into the Gt(ROSA)26Sor locus. The neo-selection cassette was removed by crossing to FlpO-expressing mice. (J:251124)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count