A CAGGS promoter, floxed stop cassette, mutant Prkag1 cDNA encoding D316A mutation, and a sequence encoding the Flag epitope at the C terminus were inserted via homologous recombination into the Gt(ROSA)26Sor locus. The neo-selection cassette was removed by crossing to FlpO-expressing mice. (J:251124)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6NCrl
Targeted
Insertion
--
--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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