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EN
A cassette of the sequence corresponding to the exons 6 and 7 of the Zf423 gene with the nucleotides 3861-4108 of the ORF deleted and an FRT flanked neomycin selection cassette replaced the endogenous exons 6 and 7. It causes a frameshift mutation that produces a stop codon 158 bp into exon 8. The resulting C-termally trancated protein lacks zinc fingers 28-30 and 91 C-terminal amino acids. (J:245759)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
